??? ?? ?????? ? ????? ???? ???? ???? ?????? ??? ??? ???‌???? ?????? ????? ??? ? ????? ????‌?? ??? ???????? ?????? ??? ?? ???? ???????? ???? ??? ? ?? ?????? ????? ?????? ?????? ?? ??? ???? ????? ? ??? ?? ???? ????. Availability of treatment method is another element. Applicants may have